Preparation And Evaluation of Mouth Dissolving Film of Fexofinadine Hydrochloride

Mouth dissolving films are at the forefront of oral solid dosage forms, offering enhanced comfort and versatility. They outperform fast-dissolving tablets by rapidly dissolving in the mouth with reduced saliva, hence enhancing the effectiveness of the active pharmaceutical ingredient (API). These films are a popular choice among consumers compared to traditional tablets or capsules because they do not require chewing or water for administration. The emerging technology of oral mouth dissolving films demonstrates significant potential due to its capacity to meet diverse requirements. The main goal of this review is to formulate and analyse mouth dissolving film containing fexofenadine hydrochloride. Children have a higher likelihood of experiencing acute rhinitis, hence fexofenadine has a synergistic effect in their treatment. The evaluation criteria include the assessment of organoleptic features, surface characteristics, tensile strength, folding endurance, thickness, drug solubility, percentage of elongation, and drug content determined using estimation techniques.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2024-12-23
DOI
https://doi.org/10.5281/zenodo.14547851
Primary Topic
Advanced Drug Delivery Systems
Type
article
Field-Weighted Citation Impact
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article

Preparation And Evaluation of Mouth Dissolving Film of Fexofinadine Hydrochloride

Zenodo (CERN European Organization for Nuclear Research)
Advanced Drug Delivery Systems
article

Preparation And Evaluation of Mouth Dissolving Film of Fexofinadine Hydrochloride

article en

Abstract

Mouth dissolving films are at the forefront of oral solid dosage forms, offering enhanced comfort and versatility. They outperform fast-dissolving tablets by rapidly dissolving in the mouth with reduced saliva, hence enhancing the effectiveness of the active pharmaceutical ingredient (API). These films are a popular choice among consumers compared to traditional tablets or capsules because they do not require chewing or water for administration. The emerging technology of oral mouth dissolving films demonstrates significant potential due to its capacity to meet diverse requirements. The main goal of this review is to formulate and analyse mouth dissolving film containing fexofenadine hydrochloride. Children have a higher likelihood of experiencing acute rhinitis, hence fexofenadine has a synergistic effect in their treatment. The evaluation criteria include the assessment of organoleptic features, surface characteristics, tensile strength, folding endurance, thickness, drug solubility, percentage of elongation, and drug content determined using estimation techniques.

Zenodo (CERN European Organization for Nuclear Research)
Openalex Percentile: Top 66%
Advanced Drug Delivery Systems
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