Case Report on Tacrolimus – Associated Pres

Posterior reversible encephalopathy syndrome (PRES) is a disorder characterized by grey and white matter abnormalities in the temporal, parietal, and occipital lobes of the brain. Clinical findings involve headache, mental status changes, focal neurological deficits, as well as visual disturbance which are also associate with characteristic imaging features of subcortical white matter lesions on computed tomography (CT) and magnetic resonance imaging (MRI). it may lead to significant morbidity and mortality if it is not diagnosed instantly. The study sheds light on importance of magnetic resonance imaging in prompt recognition of this syndrome, withholding tacrolimus may be consider to be diagnostic tool, if symptoms persists or other complications require this approach. We aimed to present our 44 years old secondary membranous nephropathy with nephrotic syndrome secondary to lupus nephritis with ANA profile S1RNP positive, right lower limb DVT provoked due to nephrotic syndrome, complicated pyelonephritis S/P D-J stent removal patient in whom we observed press following tacrolimus treatment in the light of clinical and MRI findings.