Fungal skin disorders and their alleviation using Delonix regia extract

Fungal skin disorders, caused by dermatophytes, yeasts, and molds, represent a significant global health concern, affecting millions of people worldwide. These infections often lead to symptoms such as itching, redness, and scaling, and in some cases, can result in chronic conditions if left untreated. Conventional antifungal treatments, while effective, often come with adverse effects, drug resistance, and high treatment costs. As a result, there is a growing interest in exploring alternative, natural remedies. Delonix regia (Royal Poinciana), a tropical plant known for its antimicrobial, anti-inflammatory, and antioxidant properties, has garnered attention as a potential natural alternative for treating these disorders. This study aims to aggregate the existing data on fungal skin infections and evaluate the therapeutic potential of Delonix regia extract in managing such conditions. Through in vitro and in vivo investigations, the findings suggest that Delonix regia extract demonstrates significant antifungal activity, particularly against dermatophytes, and may serve as an effective complementary treatment in managing fungal skin infections. The plant's multifaceted bioactivity, including its ability to reduce inflammation and oxidative stress, further supports its potential as a valuable adjunct to conventional antifungal therapies.