The Evolving Landscape of Obesity over the Last Decade: From Genetic Predisposition to Public Health Interventions

Abstract: Obesity has become a global problem affecting billions of the people worldwide and increase substantially overall across the world. Researchers across the globe are trying to figure out its causes, and possible intervention to control this problem. This review explores the genetic factors contributing to obesity and discusses the challenges and treatment options associated with this condition. It also aims to provide a multidisciplinary perspective on this complex problem by thoroughly assessing the genetic insights, challenges, and therapeutic options associated with obesity. This study aims to support, current techniques and advancements to combat obesity by improving this multimodal disease burden on society and healthcare. By understanding the various facets of this condition, we can work towards developing effective solutions and improving the health of individuals worldwide. Keywords: Obesity, Genes, Complications, Fat Mass and Obesity Associated Gene (FTO) Proopiomelanocortin (POMC), leptin receptor (LEPR) deficiency, melanocortin-4 (MC4) receptor agonist, genome-wide association studies, childhood obesity.