Phage display in disease diagnosis: from antibody selection to clinical translation

With the advent of molecular biology, a number of display techniques have been developed for the generation of recombinant antibodies. Phage display remains the most effective technique for generating recombinant antibodies. The key factor driving its success is the resilience of the phage particles, facilitating automation and adaptability to modifications. The production of monospecific binders provides an essential diagnostic tool at a more economical and efficient cost. Recombinant antibodies may be altered with significant versatility, rendering them highly appropriate across various platforms.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-05-14
DOI
https://doi.org/10.5281/zenodo.15401056
Primary Topic
Birth, Development, and Health
Type
article
Field-Weighted Citation Impact
0.00
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article

Phage display in disease diagnosis: from antibody selection to clinical translation

Zenodo (CERN European Organization for Nuclear Research)
Birth, Development, and Health
article

Phage display in disease diagnosis: from antibody selection to clinical translation

article en

Abstract

With the advent of molecular biology, a number of display techniques have been developed for the generation of recombinant antibodies. Phage display remains the most effective technique for generating recombinant antibodies. The key factor driving its success is the resilience of the phage particles, facilitating automation and adaptability to modifications. The production of monospecific binders provides an essential diagnostic tool at a more economical and efficient cost. Recombinant antibodies may be altered with significant versatility, rendering them highly appropriate across various platforms.

Zenodo (CERN European Organization for Nuclear Research)
Openalex Percentile: Top 46%
Birth, Development, and Health
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Phage display in disease diagnosis: from antibody selection to clinical translation · Zenodo (CERN European Organization for Nuclear Research) (2025) | TGRS Research Map | TGRS