Formulation And Evaluation of Polyherbal Antitussive Cough Syrup

The oral cavity serves as a critical interface between the external environment and the body’s internal systems, playing a fundamental role in digestion, respiration and defence against pathogens. However, its constant exposure to microbial agents makes it highly susceptible to oral infections such as halitosis, gingivitis and dental caries—conditions increasingly linked to systemic disorders like cardiovascular disease and diabetes. While mechanical cleaning methods are essential, mouthwashes provide additional antimicrobial coverage, especially in hard-to-reach areas. This project focuses on the formulation and evaluation of a herbal mouthwash utilizing scientifically validated medicinal plants including Ocimum sanctum (Tulsi), Mentha piperita (Peppermint), Zingiber officinale (Ginger) and Cinnamomum zeylanicum (Cinnamon). These ingredients were selected for their proven antimicrobial, anti-inflammatory and antioxidant properties. The study aims to develop a safe, stable and sensory-acceptable herbal formulation that promotes oral freshness and microbial protection. Evaluation involves physicochemical analysis, stability assessment and antimicrobial testing against oral pathogens. This work contributes to the advancement of natural, eco-friendly oral care solutions and supports the integration of traditional herbal wisdom with modern pharmaceutical practices.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-05-23
DOI
https://doi.org/10.5281/zenodo.15497787
Primary Topic
Natural Compound Pharmacology Studies
Type
article
Field-Weighted Citation Impact
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article

Formulation And Evaluation of Polyherbal Antitussive Cough Syrup

Zenodo (CERN European Organization for Nuclear Research)
Natural Compound Pharmacology Studies
article

Formulation And Evaluation of Polyherbal Antitussive Cough Syrup

article en

Abstract

The oral cavity serves as a critical interface between the external environment and the body’s internal systems, playing a fundamental role in digestion, respiration and defence against pathogens. However, its constant exposure to microbial agents makes it highly susceptible to oral infections such as halitosis, gingivitis and dental caries—conditions increasingly linked to systemic disorders like cardiovascular disease and diabetes. While mechanical cleaning methods are essential, mouthwashes provide additional antimicrobial coverage, especially in hard-to-reach areas. This project focuses on the formulation and evaluation of a herbal mouthwash utilizing scientifically validated medicinal plants including Ocimum sanctum (Tulsi), Mentha piperita (Peppermint), Zingiber officinale (Ginger) and Cinnamomum zeylanicum (Cinnamon). These ingredients were selected for their proven antimicrobial, anti-inflammatory and antioxidant properties. The study aims to develop a safe, stable and sensory-acceptable herbal formulation that promotes oral freshness and microbial protection. Evaluation involves physicochemical analysis, stability assessment and antimicrobial testing against oral pathogens. This work contributes to the advancement of natural, eco-friendly oral care solutions and supports the integration of traditional herbal wisdom with modern pharmaceutical practices.

Zenodo (CERN European Organization for Nuclear Research)
Openalex Percentile: Top 67%
Natural Compound Pharmacology Studies
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