Single-cell atlas of the human immune system reveals sex-specific dynamics of immunosenescence

Output data from "Single-cell atlas of the human immune system reveals sex-specific dynamics of immunosenescence": 01_DEA_Results: Differential expression analysis with age 02_Binomial_test_bias: Binomial test on the directionality of expression of differentially expressed genes with age 03_DEA_sharing: Cell type sharing of genes differentially expressed with age 04_DEA_Results_Replication_Oelen2022: Differential expression analyses with age in the replication dataset form Oelen et al., 2022 05_CompositonalAnalysis_CellType: Cell type compositional analysis with age 06_CellCycleInfo_Seurat: Cell cycle phase scoring using Seurat 07_CellCycleInfo_Tricycle: Cell cycle phase scoring using tricycle 08_CompositionalAnalysis_CellCycle_Seurat: Cell cycle phase compositional analysis with age form Seurat 09_CompositionalAnalysis_CellCycle_Tricycle: Cell cycle phase compositional analysis with age form Tricycle 10_DifferentialEnrichment_Quiescence_AUCell: Differential enrichment analysis from quiescence gene set from AUCell 11_DifferentialEnrichment_Senescence_AUCell: Differential enrichment analysis from senescence gene set from AUCell 12_DifferentialEnrichment_Senescence_SenCID: Differential enrichment analysis from senescence gene set from SenCID 13_CompostionalAnalysis_CellType_Replication_Oelen: Cell type compositional analysis with age in the replication dataset form Oelen et al., 2022 14_DEA_Results_Females: Differential expression analyses with age in females 15_DEA_Results_Males: Differential expression analyses with age in males 16_DEA_Results_Interaction: Differential expression analyses with the interaction of age:sex 17_CompositonalAnalysis_CellType_Females: Cell type compositional analysis with age in females 18_CompositonalAnalysis_CellType_Males: Cell type compositional analysis with age in males 19_CompositonalAnalysis_CellType_Interaction: Cell type compositional analysis with the interaction of age:sex 20_DifferentialAbundance_Females: Differential abundance analysis with age in females 21_DifferentialAbundance_Males: Differential abundance analysis with age in females 22_DifferentialAbundance_AllData_Subsampling1: Differential abundance analysis with age in a 25% random subsampling of the data 23_DifferentialAbundance_AllData_Subsampling2: Differential abundance analysis with age in a 25% random subsampling of the data 24_DifferentialAbundance_AllData_Subsampling3: Differential abundance analysis with age in a 25% random subsampling of the data 25_Nhood-cell_id_Females: Correspondence of each individual cell to a Milo neighborhood in females 26_Nhood-cell_id_Males: Correspondence of each individual cell to a Milo neighborhood in males 27_Nhood_Markers: Markers of age-enriched or age-depeleted milo nhoods in males and females 28_Enrichments_NhoodMarkers_Females: GO enrichments of markers from age-enriched neighborhoods in females 29_Enrichments_NhoodMarkers_Males: GO enrichments of markers from age-enriched neighborhoods in males 29_Enrichments_NhoodMarkers_Males: GO enrichments of markers from age-enriched neighborhoods in males 30_DEA_GZMB_Females: Differential expression analysis in CD8 TEM subpopulations in females 30_DEA_GZMB_Males: Differential expression analysis in CD8 TEM subpopulations in males 31_CompositonalAnalysis_CellType_GZMB_Females: Cell type compositional analysis with age for CD8 TEM subpopulations in females 32_CompositonalAnalysis_CellType_GZMB_Males: Cell type compositional analysis with age for CD8 TEM subpopulations in males 33_DEA_ISG_CD14_Mono_Females: Differential expression analysis with age in CD14 Mono subpopulations