The Art of Finding the Right Drug Target: Emerging Methods and Strategies

Compounds in bodily fluids and biological tissues that interact with medications are identified as drug targets. Discovering new targets for drugs is an essential aspect of the drug development process and is vital for producing innovative treatments in areas such as precision medicine and cancer therapy. Traditional in vitro or in vivo target-finding techniques slow down the speed of drug discovery due to the labor or time-intensive nature of the process. The advancement of discovery techniques and the implementation of various cutting-edge technologies have led to a significant improvement in the effectiveness of drug discovery, resulting in shorter cycle times and lower costs. This study encompasses novel methods for drug target identification, such as computer-assisted techniques, drug affinity response target stability, multi-omics analysis, gene editing, and nonsense-mediated m-RNA degradation.