Assessing the Safety and Efficacy of PRP in the Management of Diabetic Foot Ulcers

Background and Aim: Diabetic foot ulcers remain a critical concern worldwide, even with the progress achieved in diabetes management. Diabetic foot ulcers remain a critical global challenge, even with the progress achieved in diabetes management. Material and Methods: This study, designed as a prospective comparative analysis, focused on patients suffering from diabetic foot ulcers who were admitted to the surgical department over the course of one year. In this study, participants were categorised into two distinct groups: Group A, which was treated with conventional ordinary dressing (n=40), and Group B, which received Platelet-Rich Plasma (PRP) dressing (n=40, %). The average duration of follow-up was 6 weeks. Results: The findings from our study indicated that participants treated with PRP experienced a wound contraction rate of 22.50%, surpassing that of the group receiving conventional treatment alone. The findings were statistically significant, indicating that PRP may improve wound healing in diabetic wounds. The time needed for wound contraction in the case group was significantly shorter than that observed in the control group (p<0.05). Conclusion: The wounds of subjects receiving PRP dressing exhibited greater contraction compared to those in the non-treated group. This finding suggests that PRP dressing serves as an effective method to enhance wound contraction in diabetic patients and can be utilised alongside traditional treatment approaches for the healing of diabetic wounds.