From Desire to Performance: Comprehensive Review on Flibanserin and Sildenafil

This work aims at presenting a comparative analysis of Flibanserin an agent used to treat sexual dysfunction in women and Sildenafil an agent used to treat erectile dysfunction in men. Flibanserin is used to treat female sexual dysfunction that is known as hypoactive sexual desire disorder in women of the premenopausal age group while Sildenafil is mostly used in men to facilitate erectile dysfunction. It analyses their pharmacodynamics and pharmacokinetics, effectiveness, risk-benefit balance, tolerability, and effects upon patients. Neural inhibition of serotonin has also been seen to increase the intensity of sexual desire and libido, slightly improved with some side effects flirting with flibanserin. Sildenafil acts through enhancing the smooth muscle relaxation through inhibition of PDE5 and thus causing an increase in blood flow to the penis, and overall sildenafil has been reported to have high effectiveness coupled with relative safety in most of the male population. Awareness of the differences and specifics of these products may assist healthcare professionals in their choice of approaches to sexual dysfunction.