Role of Alvarado Score and Changes in C-Reactive Protein (CRP), S. Bilirubin and Mean Platelet Volume (MPV) in Pre-Op Diagnosis of Acute Appendicitis

Aim: The aim of the present study was to evaluate the role of Alvarado score and changes in C-reactive protein, S. bilirubin and MPV in preop diagnosis of acute appendicitis. Materials and Methods: This prospective, analytical study was conducted in the Department of General Surgery, Civil Hospital and B.J. Medical College, Ahmedabad from October 2023 to October 2024. 100 patients were selected for this study as per the inclusion and exclusion criteria, with age more than 8 years and right iliac fossa pain as the main complaint. Result: The maximum patients were in the age group of 11-30 years having 75 males and 25 females. In our study, the patients whose Alvarado score was 7 or more have the high chances of having the Acute Appendicitis. There was no significant relationship (p<0.01) between C-reactive protein, S. bilirubin and MPV with patients having Alvarado score more than 7. So, C-reactive protein, S. bilirubin and MPV are not a reliable marker in preop diagnosis of acute appendicitis. Conclusion: Alvarado score as scoring system is valuable and valid instrument of discrimination between acute appendicitis and non-specific abdominal pain. There is no role in combining the clinical (Alvarado score) and laboratory parameters for diagnosis of acute appendicitis.