Mouth Ulcer Management via Oral Films: A Critical Review of Formulation, Evaluation, and Future Directions

Mouth ulcers are a widespread and debilitating condition. Recent research suggests that riboflavin, a B-complex vitamin, may offer a promising treatment option due to its antioxidant and anti-inflammatory effects. This review delves into the development and efficacy of riboflavin oral films, a novel delivery system that enhances bioavailability and targets the affected area. We summarize the current research on riboflavin oral films, discussing their benefits, challenges, and therapeutic potential in treating mouth ulcers. This comprehensive review serves as a valuable resource for researchers, formulation scientists, and clinicians seeking to optimize riboflavin oral films for mouth ulcer treatment.