Evaluating Eye Symptoms in Psoriatic Patients: A Case-control Study

Background: Psoriasis is a persistent inflammatory condition that primarily impacts the skin, nails, and joints. While ocular manifestations are relatively uncommon in the existing literature, particularly among those with psoriatic arthritis. This study aimed to investigate the prevalence and characteristics of eye involvement in individuals diagnosed with psoriasis. Materials and Methods: The study included 134 individuals with psoriasis compared with 134 healthy participants. A comprehensive history was obtained for all participants, followed by dermatological, systemic, and ophthalmological assessments. Schirmer’s test and tear breakup time (BUT) were performed. Continuous variables were analyzed using the t-test, while categorical data were compared using the chi-square test. Logistic regression analysis was employed to explore associations between ocular findings and variables. Statistical evaluations were conducted separately for the right and left eyes. Results: Patients with psoriasis exhibited a significantly higher frequency of ocular findings in both eyes compared to the control group. Additionally, Schirmer’s and BUT values were markedly reduced in psoriasis patients compared to the controls. Conclusion: The findings underscore the importance of regular ophthalmological evaluations in patients with psoriasis for timely detection and management of ocular complications. However, further research is needed to elucidate the underlying mechanisms of ocular involvement in this patient population.