To Assess and Compare the Efficacy of Transnasal Humified Rapid Insufflation Ventilatory Exchange (Thrive) with Nasal Oxygen Supplementation for Apnoeic Oxygenation during Short Bronchoscopy Procedures

Background: Transnasal humidified rapid insufflation ventilatory exchange (THRIVE) during apnoea has shown to delay desaturation. The primary aim of the study was to assess the effectiveness of THRIVE during apnoeic oxygenation for short bronchoscopy procedures and compare it with nasal oxygen supplementation method. Method: A total 90 patients of either sex, between 12-45 years with ASA I, II undergoing short bronchoscopy procedures were enrolled in the study with two groups of 45 in each. Group N: patients received nasal cannula O2 supplementation @ 15 L/min and Group H: patients received O2 supplementation via THRIVE @ 70 L/min. Unpaired t-test was used to compare variables between two groups. Results: There was no significant difference in the mean total apnoea time and apnoea cycles between two groups with cut off apnoea time of 6 minutes. The SPO2 drop in group H was more gradual as compared to group N and was statistically significant (P=0.028) Also, there was statistically significant difference noted with EtCO2 on intubation between both the groups (P<0.00001). After intubation at the end of procedure, PaO2 was higher in Group H, but not statistically significant (P=0.083). However, there was statistically significant difference in PaCO2 noted with higher values in group N (P<0.00001). Conclusion: The oxygen supplementation for short bronchoscopy procedures during apnoeic oxygenation with THRIVE and nasal cannula were equally effective in maintaining oxygenation till six minutes of apnoea time, but PaCO2 values were seen higher in conventional nasal oxygen supplementation as compared to THRIVE at the end of procedure.