CORRECTION OF EXCRETORY FUNCTION OF THE STOMACH IN PATIENTS WITH CHRONIC RENAL FAILURE

Chronic renal failure(CRF) is a gradual deterioration of kidney function over a long period of time. In modern literature, the term "chronic kidney disease" is used, which has a slightly broader meaning and implies a decrease in kidney function over three months or more.CKD is a syndrome resulting from irreversible progressive decline in renal function caused by a decrease in the mass of their functioning parenchyma with concomitant metabolic disorders and the development of pathology in a number of organs and systems. According to the World Health Organization, more than 850 million people worldwide suffer from kidney-related diseases. Chronic kidney disease (CKD) causes 2.4 million deaths per year and is the 6th and fastest growing cause of death. The number of patients receiving dialysis treatment in the world is more than 2.5 million people. Treatment of CKD stages I-IV is aimed at reducing the rate of progression of renal failure and consists of dietary recommendations, blood pressure control, correction of anemia, hyperlipidemia and other conservative measures. Unfortunately, most diseases leading to CKD are currently incurable. The rate of progression of renal failure depends significantly on how well the patient follows the nephrologist's recommendations on diet and drug therapy. Risk factors that worsen kidney function are: uncontrolled intake of medications (antibiotics, antipyretics, painkillers, diuretics, dietary supplements), high blood pressure, alcohol. According to WHO, symptoms of atrophic gastritis with low acidity occur in 30% of the world's population, and not all of them receive appropriate treatment. People aged 40 and older are most susceptible to the disease. Low acidity is a serious problem. After all, the presence of acid in the stomach provides a bactericidal effect. With insufficient acid, such protection is significantly weakened and harmful microbes can freely enter the body along with food, disrupting the intestinal and stomach microflora. We were also interested in the issue of the excretory function of the stomach (EFG), because metabolic products (lactic acid, urea, creatinine, poisons, etc.) are excreted into the lumen of the stomach through the mucous membrane. Given the above, the study and correction of EFG in chronic renal failure is a relevant area in medicine.