Prevalence of Metabolic Syndrome in Chronic Plaque Psoriasis: A Hospital Based Case Control Study

Psoriasis is a papulosquamous, proliferative condition of the skin, in which both genetic and environmental influences have a critical role. Psoriasis with metabolic syndrome causes significant physical and psychological morbidity to the patient. Therefore, the present study was conducted to study prevalence of metabolic syndrome in chronic plaque psoriasis at tertiary care centre. The present study was case control study carried out at Department of Dermatology of tertiary care centre during November 2021 to October 2022. A total of 50 50 cases of chronic plaque psoriasis diagnosed clinically above 18 years were enrolled while 50 age and sex matched controls were included. Metabolic syndrome is defined based on the revised criteria from NCEP ATP III. The statistical software namely SPSS 22.0 used for the analysis of the data. The mean age in Cases was 40.34±12.50 years and Control was 41.50±13.28 years with no significant difference. Both the group shows male dominance. Percentage of metabolic syndrome in patients with psoriasis in cases (42%) was more as compared to controls (2%) was statistically highly significant (P<0.0001) The present study concludes that there is a significantly higher prevalence of metabolic syndrome in psoriasis patients as compared to general population.