A study on role of Serum Magnesium Levels in Preterm Labour

Introduction: Preterm labour (PTL), occurring before 37 weeks, is a major cause of neonatal morbidity. Magnesium’s role in muscle relaxation and its potential to prevent PTL has drawn attention. This study aims to investigate the relationship between serum magnesium levels and PTL to explore its predictive and therapeutic value. Methods: This cross-sectional study was conducted at GSL Medical College, Rajahmundry, from October 2018 to March 2020, involving pregnant women aged 18-45 with gestational age between 24-37 weeks. Serum magnesium levels were measured and analyzed for correlation with preterm labour outcomes using SPSS software, with a significance level of p < 0.05. Results: A total of 80 participants were included, with 46% aged 25-29 years and 73.5% having a normal BMI. Serum magnesium levels were >1.7 mg/dL in 53.75%. Significant differences were found between serum magnesium levels and labour duration, delivery, and fetal outcomes, but not with parity, gestational age, or gestation period. Conclusion: This study underscores the role of serum magnesium in predicting and managing preterm labour. Lower magnesium levels were linked to increased labour complications, while higher levels improved outcomes. Though no significant correlation was observed with parity or gestation, magnesium remains crucial for uterine function and fetal well-being in obstetric care.