Thyroid Dysfunction in Patients with Metabolic Syndrome - A Cross Sectional ObservationalStudy from a Single Centre

Aims and Objectives: The metabolic syndrome consists of a constellation of metabolic abnormalities that confer increased risk of cardiovascular disease (CVD) and diabetes mellitus. This study was to look for prevalence of thyroid dysfunction, which is known to increase the morbidity when it is associated with metabolic syndrome. Materials and Methods: An Unaccented cross sectional study was done over 18 months and patients who were over 18 years of age and those who satisfied the criteria for Metabolic Syndrome (as per NTEP ATP III criteria) were included. Patient demographics, blood investigations to include thyroid profile, lipid profile and vital data were included. Data were statistically analysed and presented. Results: In this study of 84 patients, thyroid dysfunction (Hypothyroidism/ Subclinical hypothyroid state) was prevalent in 17.9% (15/84) of metabolic syndrome patients which was statistically significant (P <0.001). Conclusion: Sublinical and to a lesser extent overt hypothyroidism is seen in patients with metabolic syndrome and early recognition and appropriate treatment is indicated.