DRUG RESISTANT EPILEPTIC ENCEPHALOPATHY WITH LATE-ONSET SPASMS

Developmental and epileptic encephalopathy (DEE) is a term used to describe cerebral dysfunction resulting from the underlying cause, epilepsy, or both. There is a subset of DEEs in which there is compelling evidence that the regression is directly tied to the epilepsy itself, where the “epileptic encephalopathy” component of DEE is most evident. Infantile epileptic spasm syndrome (IESS) is perhaps the clearest example.