A STUDY OF EFFECTS OF VITAMIN C & VITAMIN E SUPPLEMENTATION ON NUTRITIONAL ANAEMIA IN TERTIARY CARE HOSPITAL

Abstract Objective: Nutritional anaemia, one of the most common global health concerns, is associated with an increase in free radicals. Antioxidants, such as vitamin C & vitamin E are known for their beneficial effects on oxidative stress. The study was conducted with the aim of studying the combined effects of vitamins C & E on the treatment of iron deficiency anaemia (IDA). Materials & Methods: A total of 140 patients with known IDA were studied in the Department of Physiology Santosh Medical College in collaboration with the Department of Medicine Sharda Hospital. These patients were divided into 2 groups each of 70 per group. The control group was treated with ferrous sulphate and the test group was treated with ferrous sulphate, vitamin C and vitamin E. Complete blood counts of all the patients were measured before and after treatment and the data was statistically analysed. Results: Patients in both groups demonstrated statistically significant improvement in their Hb, MCV, and MCHC levels, suggesting improvement in IDA. This improvement was higher in patients taking Vitamin C & E compared to the patients taking ferrous sulphate alone. Haematological parameters, such as TIBC, Serum Ferritin and RDW also established a better improvement in iron storage in patients taking antioxidants. Conclusion: The study demonstrated that administrating antioxidants, in conjunction with ferrous sulphate, in the treatment of IDA could provide better results.