THE ROLE OF BILIRUBIN AS A CARDIOPROTECTIVE AGENT (LITERATURE REVIEW)
: The prevalence of cardiovascular diseases is escalating and the need for new prognostic markers is growing. Bilirubin, a breakdown product of hemoglobin, has antioxidant and antiinflammatory properties, which may play a significant role in protecting the heart. Elevated bilirubin levels are tied to a diminished risk of coronary heart disease, which has been confirmed by numerous studies. In this publication, we will discuss the cardioprotective properties of bilirubin, its physiological mechanisms of myocardial defense against ischemia, as well as genetic determinants.
Publication Details
- Journal
- Zenodo (CERN European Organization for Nuclear Research)
- Published
- 2024-11-10
- DOI
- https://doi.org/10.5281/zenodo.14098547
- Primary Topic
- Heme Oxygenase-1 and Carbon Monoxide
- Type
- article
- Field-Weighted Citation Impact
- 0.00