Cardiovascular Diseases and Apical Periodontitis, Connection of Two Pathologies in Adult Patients; A Systematic Review

Objectives: The objective of this research was to examine the potential relationship between apical periodontitis and arteriosclerosis. Materials and Methods: A specific query was applied to the Pubmed page containing medical articles. Three independent reviewers were tasked with the collection and selection of articles for inclusion in the study. The selected data items consisted of the year of publication of the article, the article's purpose, the specific name of the bacterium, the causes of endodontic pathology, and the definitive or evasive conclusion of the published article. Results: The present study included a total of 25 articles. Four review-type studies were identified that demonstrated a positive correlation between apical periodontitis and cardiac diseases. Articles primarily focused on the association between apical periodontitis and cardiovascular diseases, without specifying a specific bacterial strain. The available data suggests that the combination of cardiac examinations and blood tests is the most prevalent methodology employed. A strong or relative interconnection was observed between the pathologies of apical periodontitis and cardiac diseases. Conclusion: Research indicates that there is a notable correlation between apical periodontitis and cardiac pathologies. It is worth noting that the inflammatory markers found in blood are not specific enough to enable the accurate diagnosis of apical periodontitis.