Drug Resistance in People With Viremia on Dolutegravir-based Antiretroviral Therapy in Sub-Saharan Africa: The DTG RESIST Study.

Dolutegravir resistance is an increasing concern. An analysis of the DTG RESIST study found that among 227 integrase sequences from 7 African countries (all non-B subtypes), 59 (26.0%) had at least 1 major drug resistance mutation (primarily G118R and E138A/K/T), with 49 (21.6%) predicted to have high-level resistance to dolutegravir.

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Publication Details

Journal
Open Access CRIS of the University of Bern
Published
2025-05-20
DOI
https://doi.org/10.48620/89528
Primary Topic
Sports Performance and Training
Type
article
Field-Weighted Citation Impact
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article

Drug Resistance in People With Viremia on Dolutegravir-based Antiretroviral Therapy in Sub-Saharan Africa: The DTG RESIST Study.

Open Access CRIS of the University of Bern
Sports Performance and Training
article

Drug Resistance in People With Viremia on Dolutegravir-based Antiretroviral Therapy in Sub-Saharan Africa: The DTG RESIST Study.

article en

Abstract

Dolutegravir resistance is an increasing concern. An analysis of the DTG RESIST study found that among 227 integrase sequences from 7 African countries (all non-B subtypes), 59 (26.0%) had at least 1 major drug resistance mutation (primarily G118R and E138A/K/T), with 49 (21.6%) predicted to have high-level resistance to dolutegravir.

Open Access CRIS of the University of Bern
Institut für Soziale Arbeit (DE)
Good health and well-being
Openalex Percentile: Top 46%
Sports Performance and Training
DOIOpen Access PDFOpenAlex
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Drug Resistance in People With Viremia on Dolutegravir-based Antiretroviral Therapy in Sub-Saharan Africa: The DTG RESIST Study. · Open Access CRIS of the University of Bern (2025) | TGRS Research Map | TGRS