[Foetal paraspinal neuroblastoma: A case report of autopsy findings].

Neuroblastoma is a rare tumour originating from neural crest cells, primarily occurring in the adrenal glands and sympathetic ganglia, with prenatal diagnosis often complicated by the difficulty in distinguishing it from other foetal abdominal or paraspinal masses. We present a case of foetal neuroblastoma in a 26-year old woman who, at 36 weeks of gestation, experienced absent foetal movements, leading to ultrasound confirmation of foetal demise with associated effusions. An emergency caesarean section revealed a stillborn male foetus with a previously undetected encapsulated mass in the posterior mediastinum, which was confirmed as neuroblastoma through histopathological analysis. This case highlights the challenges in prenatal diagnosis, as the tumour went unnoticed despite routine imaging. It contributes to the limited literature on foetal neuroblastoma, underscoring the need for further research on effective management strategies.

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Publication Details

Journal
Open Access CRIS of the University of Bern
Published
2025-01-15
DOI
https://doi.org/10.48620/84669
Primary Topic
Pesticide Residue Analysis and Safety
Type
article
Field-Weighted Citation Impact
0.00
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article

[Foetal paraspinal neuroblastoma: A case report of autopsy findings].

Open Access CRIS of the University of Bern
Pesticide Residue Analysis and Safety
article

[Foetal paraspinal neuroblastoma: A case report of autopsy findings].

article en

Abstract

Neuroblastoma is a rare tumour originating from neural crest cells, primarily occurring in the adrenal glands and sympathetic ganglia, with prenatal diagnosis often complicated by the difficulty in distinguishing it from other foetal abdominal or paraspinal masses. We present a case of foetal neuroblastoma in a 26-year old woman who, at 36 weeks of gestation, experienced absent foetal movements, leading to ultrasound confirmation of foetal demise with associated effusions. An emergency caesarean section revealed a stillborn male foetus with a previously undetected encapsulated mass in the posterior mediastinum, which was confirmed as neuroblastoma through histopathological analysis. This case highlights the challenges in prenatal diagnosis, as the tumour went unnoticed despite routine imaging. It contributes to the limited literature on foetal neuroblastoma, underscoring the need for further research on effective management strategies.

Open Access CRIS of the University of Bern
Tissue Genetics (United States) (US)
Good health and well-being
Openalex Percentile: Top 50%
Pesticide Residue Analysis and Safety
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[Foetal paraspinal neuroblastoma: A case report of autopsy findings]. · Open Access CRIS of the University of Bern (2025) | TGRS Research Map | TGRS