Long-Term Outcomes of Antegrade Thoracic Stent Grafting During Repair of Acute DeBakey I Dissection.

Background We aim to evaluate the impact of antegrade stenting of the distal arch and proximal descending aorta combined with non-total arch procedures in acute type A aortic dissection.Methods From 2005 to 2022, 733 non-syndromic patients presented with acute DeBakey type I aortic dissection and underwent non total arch procedure. Ninety-five patients underwent antegrade stenting and 638 did not. Propensity-score analysis was performed, and 95 optimal pairs were created. Survival was estimated using the Kaplan-Meier method and cumulative incidence of reintervention with death as a competing event was calculated and compared using Gray's method.Results Survival estimates at 10 years after propensity score matching were similar between both group 58.9% (95%CI: 46.5-74.5) versus 58.4% (95%CI: 48.3-70.6) (p=0.6) in the non-stented versus stented group respectively. Cumulative incidence of reintervention with competing risk of death at 10 years after propensity matching was 27% (95%CI: 17-37) versus 22% (95%CI: 14-32) (p=0.44).Conclusions Antegrade TEVAR may be beneficial for remodeling and facilitating future endovascular reinterventions and reduces the occurence of reintervention for malperfusion.

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Publication Details

Journal
Open Access CRIS of the University of Bern
Published
2024-09-19
DOI
https://doi.org/10.48620/7387
Primary Topic
Virus-based gene therapy research
Type
article
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article

Long-Term Outcomes of Antegrade Thoracic Stent Grafting During Repair of Acute DeBakey I Dissection.

Open Access CRIS of the University of Bern
Virus-based gene therapy research
article

Long-Term Outcomes of Antegrade Thoracic Stent Grafting During Repair of Acute DeBakey I Dissection.

article en

Abstract

Background We aim to evaluate the impact of antegrade stenting of the distal arch and proximal descending aorta combined with non-total arch procedures in acute type A aortic dissection.Methods From 2005 to 2022, 733 non-syndromic patients presented with acute DeBakey type I aortic dissection and underwent non total arch procedure. Ninety-five patients underwent antegrade stenting and 638 did not. Propensity-score analysis was performed, and 95 optimal pairs were created. Survival was estimated using the Kaplan-Meier method and cumulative incidence of reintervention with death as a competing event was calculated and compared using Gray's method.Results Survival estimates at 10 years after propensity score matching were similar between both group 58.9% (95%CI: 46.5-74.5) versus 58.4% (95%CI: 48.3-70.6) (p=0.6) in the non-stented versus stented group respectively. Cumulative incidence of reintervention with competing risk of death at 10 years after propensity matching was 27% (95%CI: 17-37) versus 22% (95%CI: 14-32) (p=0.44).Conclusions Antegrade TEVAR may be beneficial for remodeling and facilitating future endovascular reinterventions and reduces the occurence of reintervention for malperfusion.

Open Access CRIS of the University of Bern
United Heart and Vascular Clinic (US)
Good health and well-being
Openalex Percentile: Top 60%
Virus-based gene therapy research
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