Breakthroughs in dendritic cell-cytokine-induced killer therapy for non-small cell lung cancer

With the increasing adoption of immunotherapy in oncology, dendritic cell-cytokine-induced killer (DC-CIK) autologous cell immunotherapy has emerged as a promising strategy for the treatment of non-small cell lung cancer (NSCLC). This approach leverages the patient’s immune system by stimulating the proliferation and activation of T lymphocytes, thereby enhancing the anti-tumor immune responses. Clinical trials have demonstrated notable improvements in both immunological outcomes and clinical efficacy, with DC-CIK therapy contributing to prolonged survival and improved quality of life for NSCLC, while maintaining an acceptable safety profile. Despite these advancements, challenges remain, necessitating further comprehensive clinical studies to establish the long-term efficacy and survival benefits of DC-CIK therapy.

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Publication Details

Journal
SHILAP Revista de lepidopterología
Published
2025-03-01
DOI
https://doi.org/10.3969/j.issn.1674-7593.2025.02.016
Primary Topic
Transgenic Plants and Applications
Type
article
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article

Breakthroughs in dendritic cell-cytokine-induced killer therapy for non-small cell lung cancer

SHILAP Revista de lepidopterología
Transgenic Plants and Applications
article

Breakthroughs in dendritic cell-cytokine-induced killer therapy for non-small cell lung cancer

article en

Abstract

With the increasing adoption of immunotherapy in oncology, dendritic cell-cytokine-induced killer (DC-CIK) autologous cell immunotherapy has emerged as a promising strategy for the treatment of non-small cell lung cancer (NSCLC). This approach leverages the patient’s immune system by stimulating the proliferation and activation of T lymphocytes, thereby enhancing the anti-tumor immune responses. Clinical trials have demonstrated notable improvements in both immunological outcomes and clinical efficacy, with DC-CIK therapy contributing to prolonged survival and improved quality of life for NSCLC, while maintaining an acceptable safety profile. Despite these advancements, challenges remain, necessitating further comprehensive clinical studies to establish the long-term efficacy and survival benefits of DC-CIK therapy.

SHILAP Revista de lepidopterología
Union Hospital (HK), Shanghai Jiao Tong University (CN), Union Hospital (CN)
Good health and well-being
Openalex Percentile: Top 52%
Transgenic Plants and Applications
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