“FORMULATION, CHARACTERIZATION AND IN VITRO EVALUATION OF BETULINIC ACID-LOADED LIPID NANOCARRIERS FOR ENHANCED BIOAVAILABILITY AND SUSTAINED RELEASE IN LUNG CANCER THERAPY”
Betulinic Acid, a bioactive compound with significant anticancer potential, suffers from poor solubility and low bioavailability, limiting its therapeutic efficacy. This study aimed to develop Betulinic Acid-loaded lipid nanocarriers (BALNCs) to enhance drug solubility, bioaccessibility, and controlled release. With particle diameters between 42 and 44 nm, a polydispersity index (PDI) of approximately 0.26, and a zeta potential of approximately 20 mV, the nanocarriers were effectively synthesised and characterised, guaranteeing stability.
Institutions
- Rashtrasant Tukadoji Maharaj Nagpur University (IN)
- Nagpur Institute of Technology (IN)
- Lala Lajpat Rai Memorial Medical College (IN)
- Tamil Nadu Dr. M.G.R. Medical University (IN)
- Yashwantrao Chavan Maharashtra Open University (IN)
- Sri Balaji Vidyapeeth University (IN)
- Orthopaedic Research Group (IN)
- Bharati Vidyapeeth (Deemed to be University) (IN)
Publication Details
- Journal
- Cuestiones de Fisioterapia
- Published
- 2025-02-20
- DOI
- https://doi.org/10.48047/jr94mm57
- Primary Topic
- Aquatic Invertebrate Ecology and Behavior
- Type
- article
- Field-Weighted Citation Impact
- 0.00