Application of molecular biomarker-based support protocol in elderly glioma patients undergoing surgery

[Objective] To explore the efficacy of a molecular biomarker-based support protocol in elderly glioma patients undergoing surgery. [Methods] A total of 120 elderly patients with glioma who underwent surgery in the First Affiliated Hospital of Harbin Medical University from January 2022 to January 2024 were selected as the study subjects,and they were divided into two groups according to the random number table, with 60 cases in each group. Routine treatment support program was used in the control group, and molecular marker-based support program was used in the observation group. Postoperative recovery, complications and quality of life were compared between the two groups. [Results] The postoperative hospital stay, incision healing time, first feeding time and first water intake time in observation group were shorter than those in control group, the total cost of hospitalization and serum albumin level at 3 d after operation were higher than that in control group, the vomiting frequency at 3 h after operation, pain score at 3 d after operation were lower than those in control group, the total incidence rate of postoperative complications was lower than that in control group, the quality of life score at 3 months after operation in observation group was higher than that in control group, and the differences had statistical significance (P<0.05). [Conclusion] A molecular biomarker-based support protocol can better promote postoperative recovery, reduce the risk of complications, and improve the quality of life in elderly glioma patients undergoing surgery，but it is also relatively expensive.