Raised metal-ion concentrations after tumor resections and reconstruction with megaprotheses around the knee joint

Objectives: In arthroplasty patients serum metal ions as cobalt or chromium have been shown to be raised especially in metal-on-metal joint replacements. But also megaprostheses as used in patients with bone or soft tissue tumors have an elevated risk of raised ion concentrations even without metal-on-metal [for full text, please go to the a.m. URL]