Fine-Tuned BERT Models for Medical Entity Extraction

The exponential growth of unstructured clinical data poses significant challenges for extracting meaningful insights essential for patient care, research, and operational efficiency. This study investigates the application of transformer-based language models specifically fine-tuned BERT variants for Medical Named Entity Recognition (NER), with a focus on extracting critical entities such as diseases, medications, and procedures from biomedical text. The research explores the effectiveness of domain-adapted models like BioBERT, ClinicalBERT, and PubMedBERT, emphasizing their superior contextual understanding and performance over general-purpose models. A robust experimental design leveraging the PubMed 200k RCT dataset is employed, with model architectures ranging from traditional TF-IDF with Random Forest to advanced token-based, character-based, and hybrid Bidirectional LSTM models. Through a comprehensive evaluation using precision, recall, and F1-score, the hybrid model demonstrated the highest accuracy and robustness, particularly in handling complex and ambiguous sentence structures. Integration with medical ontologies such as SNOMED CT and RxNorm further enhanced model interpretability and interoperability. The paper also addresses ethical considerations, including bias mitigation, privacy, and regulatory compliance. Future directions include the adoption of multimodal data, federated learning, explainable AI, and real-time adaptive models. The findings underscore the transformative potential of fine-tuned BERT models in structuring clinical narratives, ultimately contributing to safer, more efficient, and data-driven healthcare systems.

Publication Details

Journal
ScholarSphere (Penn State Libraries)
Published
2025-04-23
DOI
https://doi.org/10.26207/4q6x-3575
Primary Topic
Protist diversity and phylogeny
Type
article
Field-Weighted Citation Impact
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article

Fine-Tuned BERT Models for Medical Entity Extraction

ScholarSphere (Penn State Libraries)
Protist diversity and phylogeny
article

Fine-Tuned BERT Models for Medical Entity Extraction

article en

Abstract

The exponential growth of unstructured clinical data poses significant challenges for extracting meaningful insights essential for patient care, research, and operational efficiency. This study investigates the application of transformer-based language models specifically fine-tuned BERT variants for Medical Named Entity Recognition (NER), with a focus on extracting critical entities such as diseases, medications, and procedures from biomedical text. The research explores the effectiveness of domain-adapted models like BioBERT, ClinicalBERT, and PubMedBERT, emphasizing their superior contextual understanding and performance over general-purpose models. A robust experimental design leveraging the PubMed 200k RCT dataset is employed, with model architectures ranging from traditional TF-IDF with Random Forest to advanced token-based, character-based, and hybrid Bidirectional LSTM models. Through a comprehensive evaluation using precision, recall, and F1-score, the hybrid model demonstrated the highest accuracy and robustness, particularly in handling complex and ambiguous sentence structures. Integration with medical ontologies such as SNOMED CT and RxNorm further enhanced model interpretability and interoperability. The paper also addresses ethical considerations, including bias mitigation, privacy, and regulatory compliance. Future directions include the adoption of multimodal data, federated learning, explainable AI, and real-time adaptive models. The findings underscore the transformative potential of fine-tuned BERT models in structuring clinical narratives, ultimately contributing to safer, more efficient, and data-driven healthcare systems.

ScholarSphere (Penn State Libraries)
Quality Education
Openalex Percentile: Top 59%
Protist diversity and phylogeny
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