Integrated analysis of genetic polymorphism in the Cox-2 promoter and protein expression in urine samples from patients with cisplatin resistance
Introduction: A known target of the NFκB transcription factor complex is the promoter region of Cyclooxygenase 2 (Cox-2). Overexpression of Cox-2 is particularly associated with the development of cisplatin resistance. Mxi-2 forms a complex with the NFκB p65 subunit. It is now being investigated [for full text, please go to the a.m. URL]
Institutions
- Klinik und Poliklinik für Urologie (DE)
- LVR-Klinik Köln (DE)
- Centrum für Integrierte Onkologie (DE)
Publication Details
- Journal
- German Medical Science (German Research Foundation)
- Published
- 2025-04-02
- DOI
- https://doi.org/10.3205/25nrwgu47
- Primary Topic
- NF-κB Signaling Pathways
- Type
- article
- Field-Weighted Citation Impact
- 0.00