Mitochondrial Regulation of T-cell Antitumor Immunity and Aging

This study aims to investigate the role of mitochondrial dysfunction in T-cell immunity, focusing on its effects on tumor control, aging processes, and systemic immune regulation. Using an inducible mouse model with reversible mitochondrial DNA depletion, we will explore metabolic pathways, immune cell functions, and therapeutic interventions.

Publication Details

Journal
Bundesinstitut für Risikobewertung Fachgruppe ZEBET - Datenbank und Informationsbeschaffung Abteilung Experimentelle Toxikologie und ZEBET
Published
2024-12-13
DOI
https://doi.org/10.17590/asr.0000376
Primary Topic
Inclusion and Disability in Education and Sport
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Mitochondrial Regulation of T-cell Antitumor Immunity and Aging

Bundesinstitut für Risikobewertung Fachgruppe ZEBET - Datenbank und Informationsbeschaffung Abteilung Experimentelle Toxikologie und ZEBET
Inclusion and Disability in Education and Sport
article

Mitochondrial Regulation of T-cell Antitumor Immunity and Aging

article en

Abstract

This study aims to investigate the role of mitochondrial dysfunction in T-cell immunity, focusing on its effects on tumor control, aging processes, and systemic immune regulation. Using an inducible mouse model with reversible mitochondrial DNA depletion, we will explore metabolic pathways, immune cell functions, and therapeutic interventions.

Bundesinstitut für Risikobewertung Fachgruppe ZEBET - Datenbank und Informationsbeschaffung Abteilung Experimentelle Toxikologie und ZEBET
Good health and well-being
Openalex Percentile: Top 41%
Inclusion and Disability in Education and Sport
DOIOpen Access PDFOpenAlex
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Mitochondrial Regulation of T-cell Antitumor Immunity and Aging · Bundesinstitut für Risikobewertung Fachgruppe ZEBET - Datenbank und Informationsbeschaffung Abteilung Experimentelle Toxikologie und ZEBET (2024) | TGRS Research Map | TGRS