Parameters for the migalastat PBPK models in humans.

<p>CLspec, specific clearance; K<sub>d</sub>, equilibrium dissociation constant; K<sub>off</sub>, off rate constant; PBPK, physiologically based pharmacokinetic analysis; pKa, negative base-10 logarithm of the acid dissociation constant; UDPGT, uridine diphosphate glucuronosyltransferase.</p> <p>(PDF)</p>

Publication Details

Journal
Figshare
Published
2024-12-05
DOI
https://doi.org/10.1371/journal.pone.0314030.s003
Primary Topic
Pharmacogenetics and Drug Metabolism
Type
article
Field-Weighted Citation Impact
0.00
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article

Parameters for the migalastat PBPK models in humans.

Figshare
Pharmacogenetics and Drug Metabolism
article

Parameters for the migalastat PBPK models in humans.

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Abstract

<p>CLspec, specific clearance; K<sub>d</sub>, equilibrium dissociation constant; K<sub>off</sub>, off rate constant; PBPK, physiologically based pharmacokinetic analysis; pKa, negative base-10 logarithm of the acid dissociation constant; UDPGT, uridine diphosphate glucuronosyltransferase.</p> <p>(PDF)</p>

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Openalex Percentile: Top 57%
Pharmacogenetics and Drug Metabolism
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