The adjusted cumulative incidence curves across strata defined by polygenic risk score.

Low polygenic risk score (PRS) corresponds to the bottom quintile, medium PRS is defined as quintile 2–4, and high PRS includes individuals in the top quintile in the CKB cohort. Cumulative incidence was estimated using Cox regression models with the adjustment of age, sex (if applicable), region, and the top 10 principal components. PRS, polygenic risk score; CKB, China Kadoorie Biobank. (DOCX)

Publication Details

Journal
Figshare
Published
2025-02-28
DOI
https://doi.org/10.1371/journal.pmed.1004534.s030
Primary Topic
Education Methods and Technologies
Type
article
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The adjusted cumulative incidence curves across strata defined by polygenic risk score.

Figshare
Education Methods and Technologies
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The adjusted cumulative incidence curves across strata defined by polygenic risk score.

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Abstract

Low polygenic risk score (PRS) corresponds to the bottom quintile, medium PRS is defined as quintile 2–4, and high PRS includes individuals in the top quintile in the CKB cohort. Cumulative incidence was estimated using Cox regression models with the adjustment of age, sex (if applicable), region, and the top 10 principal components. PRS, polygenic risk score; CKB, China Kadoorie Biobank. (DOCX)

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Education Methods and Technologies
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The adjusted cumulative incidence curves across strata defined by polygenic risk score. · Figshare (2025) | TGRS Research Map | TGRS