Observation and factor analysis of submucosal injection of dexamethasone for analgesia and detumescence after incremental bone implantation

Objective To study the efficacy of submucosal injection of dexamethasone in analgesia and detumescence after incremental bone implantation, and to analyze the related factors of pain and swelling after incremental bone implantation. Methods Patients with dentition defect requiring bone increment(GBR or internal maxillary sinus lift)were collected from the Special Clinic of the Affiliated Stomatology Hospital of Nanjing Medical University from January 2023 to December 2023. Pain and swelling within 72 hours after surgery were measured and recorded, as well as possible influencing factors, including gender, age, number of implants, duration of surgery, and other factors. Oral health status, pre-FAC tension and PSQ pain sensitivity were compared between the two groups at different time. Pearson correlation and multiple linear regression analysis were performed for the possible influencing factors. Results Patients receiving dexamethasone intervention had significantly lower pain levels at 12 hours and significantly lower swelling scores at 48 hours. Correlation analysis and regression analysis showed that GBR had a significant effect on postoperative pain and swelling(r=0.348, P=0.030/r=0.441, P=0.005), and the linear regression model of pain degree was also statistically significant(R2=0.126, P=0.030). Conclusion Submucosal injection of dexamethasone can significantly relieve the pain, swelling and discomfort of patients after incremental bone implantation, and improve the comfort of diagnosis and treatment.