Research advances in platinum resistance and its treatment in ovarian cancer

Ovarian cancer is one of the most malignant gynecological tumors. Platinum-based chemotherapy is an important part of ovarian cancer treatment, with platinum resistance as a difficult problem in ovarian cancer treatment. Platinum resis-tance is a complex process involving a variety of mechanisms. This article reviews the molecular mechanisms of platinum resistance in ovarian cancer cells and the advances in treatment, in order to provide a reference for the clinical treatment of this disease.