The number of Purkinje cells of the cerebellum is not affected by loss of PHF6.

<p>(A) Representative image of the cerebellum of N = 3 <i>Phf6</i><sup><i>+/Y</i></sup><i>;Nes-cre</i><sup><i>Tg/+</i></sup> and 3 <i>Phf6</i><sup><i>lox/Y</i></sup><i>;Nes-cre</i><sup><i>Tg/+</i></sup> brain. Scale bar = 200 μm. (B) Quantification of the number of Purkinje cells in the cerebellum in three mice per genotype (aged 394 to 483 days old). Cells were counted in 4 evenly spaced sections per animal. Data are presented as the number of Purkinje cells per length of the Purkinje cell layer in mm showing the results from individual animals as a circle and the mean ± sem for each genotype. Data were analysed using a two-tailed Student’s t-test (p = 0.17).</p> <p>(PDF)</p>