ABX treatment induces a state of mild intestinal inflammation in mice.

<p>Stool consistency (<b>A</b>) and occult blood in the stool (<b>B</b>) were detected daily in mice that received ABX treatment but did not receive DSS treatment. Mice present ABX treatment during the induction of colitis exhibits an earlier onset of (<b>C</b>) diarrhea and (<b>D</b>) rectal bleeding compared to mice without ABX treatment. The data shown are means ± SD. Representative results from one out of two independent experiments with n = 5. *<i>P</i> < 0.05 compared to DSS group. ABX: antibiotic treated; Ts, <i>T</i>. <i>spiralis</i> infected; ABXTs: <i>T</i>. <i>spiralis</i> infected and antibiotic treated; DSS: DSS- induced colitis; ABX-DSS: antibiotic- treated and DSS- induced colitis</p> <p>(DOC)</p>

Publication Details

Journal
Figshare
Published
2024-11-04
DOI
https://doi.org/10.1371/journal.pntd.0012645.s002
Primary Topic
Inflammatory Bowel Disease
Type
article
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article

ABX treatment induces a state of mild intestinal inflammation in mice.

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Inflammatory Bowel Disease
article

ABX treatment induces a state of mild intestinal inflammation in mice.

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Abstract

<p>Stool consistency (<b>A</b>) and occult blood in the stool (<b>B</b>) were detected daily in mice that received ABX treatment but did not receive DSS treatment. Mice present ABX treatment during the induction of colitis exhibits an earlier onset of (<b>C</b>) diarrhea and (<b>D</b>) rectal bleeding compared to mice without ABX treatment. The data shown are means ± SD. Representative results from one out of two independent experiments with n = 5. *<i>P</i> < 0.05 compared to DSS group. ABX: antibiotic treated; Ts, <i>T</i>. <i>spiralis</i> infected; ABXTs: <i>T</i>. <i>spiralis</i> infected and antibiotic treated; DSS: DSS- induced colitis; ABX-DSS: antibiotic- treated and DSS- induced colitis</p> <p>(DOC)</p>

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