Effect of <i>Phf6</i> mutation on the incidence hydrocephalus with enlarged skull.

<p>(A) Incidence of hydrocephalus with enlarged skull of N = 205 female <i>Phf6</i><sup><i>+/+</i></sup> and 268 female <i>Phf6</i><sup><i>+/–</i></sup> mice. (B) Incidence of hydrocephalus with enlarged skull of N = 104 female <i>Phf6</i><sup><i>+/+</i></sup><i>;Nes-cre</i><sup><i>Tg/+</i></sup> and 101 female <i>Phf6</i><sup><i>+/lox</i></sup><i>;Nes-cre</i><sup><i>Tg/+</i></sup>. No significant difference was detected. (C) Incidence of hydrocephalus with enlarged skull of N = 109 male <i>Phf6</i><sup><i>+/Y</i></sup><i>;Nes-cre</i><sup><i>Tg/+</i></sup> and 74 male <i>Phf6</i><sup><i>lox/Y</i></sup><i>;Nes-cre</i><sup><i>Tg/+</i></sup>. No significant difference was detected. Checked points indicate mice that were euthanized for reasons other than hydrocephalus. Data were analysed by Mantel-Cox log-rank test.</p> <p>(PDF)</p>