TMSCl-Promoted Sulfonylation\nof Propargylic Alcohols\nwith Sodium Sulfinates for the Construction of (<i>E</i>)‑1,3-Disulfonylpropenes and (<i>E</i>)‑1-Sulfonylpropenols

A direct and novel transformation of propargylic alcohols\nwith\nsodium sulfinates for the regio- and stereoselective synthesis of\n(<i>E</i>)-1,3-disulfonylpropenes and (<i>E</i>)-1-sulfonylpropenols was successfully developed in the presence\nof TMSCl under mild conditions. The preliminary mechanistic experiments\ndemonstrated that the reaction underwent an unprecedented dual nucleophilic\nsubstitution/radical addition process, in which sodium sulfinates\nwere used not only as nucleophiles but also as a sulfonyl radical\nsource.