Talauromides\nA–G, Nitrogen-Containing Heptacyclic\nOligophenalenone Dimers from the Soil Fungus <i>Talaromyces stipitatus</i> BMC-16

Seven new nitrogen-containing heptacyclic oligophenalenone\ndimers,\ntalauromides A–G (<b>1</b>-<b>7</b>), together\nwith known compounds bacillisporins A and B (<b>8</b> and <b>9</b>), talaromycesones C and B (<b>10</b> and <b>11</b>), duclauxin (<b>12</b>) and lamellicolic anhydride (<b>13</b>), were isolated from the soil derived-fungus <i>Talaromyces\nstipitatus</i> BMC-16. Their chemical structures were determined\nbased on spectroscopic analysis data. The absolute configurations\nwere elucidated by chemical approaches and the comparison of CD spectra\nwith related compounds. Compounds <b>3</b>, <b>8</b> and <b>11</b> exhibited inhibitory activity on the Wnt/β-catenin\nsignaling pathway in zebrafish embryos at a concentration of 20 μM.