Multifunctional\nZnO-Loaded Colloidosomes with Multiple\nSynergies as a UV Filter

ZnO\nnanoparticles with high safety and stability are often used\nas active ingredients in sunscreens to protect the skin from ultraviolet\nrays. However, ZnO nanoparticles are easy to agglomerate, which will\nsignificantly affect the ultraviolet absorption and bacteriostatic\nproperties, and the reactive oxygen species induced by the photocatalytic\nactivity may result in irreversible secondary damage to the skin.\nHerein, the ZnO nanoparticles are dispersed uniformly on the surface\nof latex particles, and these composite particles are used as shell\nmaterials to construct self-assembled colloidosomes by high-gravity\ntechnology, which can improve the application properties with synergistic\nenrichment of the hollow structure. The ultraviolet resistance of\ncolloidosomes is significantly higher than that of the pure ZnO nanoparticles.\nThe higher the loading capacity, the more obvious the inhibition effect\nof colloidosomes on the growth of <i>Gram</i> bacteria.\nFurthermore, the antioxidant anthocyanin is in situ encapsulated in\ncolloidosomes, and at a concentration of 2 g/L, the high free radical\nscavenging rate of 78% can be achieved. The construction of multifunctional\ncolloidosomes provides a route for sunscreen and cosmetics applications.