Two new meroterpenoids from the gum resin of Ferula ammoniacum (D.Don) Spalik, M.Panahi, Piwczyński & Puchałka

The gum of Ferula ammoniacum (D.Don) Spalik, M.Panahi, Piwczyński & Puchałka is an herbal remedy used in traditional medicines for its effectiveness against various ailments. The phytochemical analysis of the ethyl acetate extract of the gum ammoniacum led to the discovery of two novel meroterpene derivatives 1 and 2. The structural elucidation of these isolated compounds was accomplished though 1D and 2D NMR spectroscopy, and HRESIMS, alongside comparison with existing literature data. Compound 1 represents a previously unreported meroterpenoid with a unique natural skeleton. A plausible biosynthetic pathway for this compound has also been proposed.