Automated Spectral Optimization of Selective Trabeculoplasty (SLT) Laser Parameters via Adaptive Bayesian Reinforcement Learning

**Abstract:** This paper presents a novel system for automated optimization of Selective Trabeculoplasty (SLT) laser treatment parameters. Leveraging adaptive Bayesian Reinforcement Learning (ABRL) integrated with real-time optical coherence tomography (OCT) feedback, our system dynamically adjusts laser spot size, power, and pulse duration to achieve superior intraocular pressure (IOP) reduction and minimal collateral damage. The method minimizes trial-and-error in clinical settings, accelerating treatment and improving patient outcomes within the established safety profile of SLT. We demonstrate the viability and potential improvement over existing manual procedures through simulation and retrospective data analysis, projecting significant long-term benefits for glaucoma treatment.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-08-08
DOI
https://doi.org/10.5281/zenodo.16779188
Primary Topic
Glaucoma and retinal disorders
Type
article
Field-Weighted Citation Impact
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article

Automated Spectral Optimization of Selective Trabeculoplasty (SLT) Laser Parameters via Adaptive Bayesian Reinforcement Learning

Zenodo (CERN European Organization for Nuclear Research)
Glaucoma and retinal disorders
article

Automated Spectral Optimization of Selective Trabeculoplasty (SLT) Laser Parameters via Adaptive Bayesian Reinforcement Learning

article en

Abstract

**Abstract:** This paper presents a novel system for automated optimization of Selective Trabeculoplasty (SLT) laser treatment parameters. Leveraging adaptive Bayesian Reinforcement Learning (ABRL) integrated with real-time optical coherence tomography (OCT) feedback, our system dynamically adjusts laser spot size, power, and pulse duration to achieve superior intraocular pressure (IOP) reduction and minimal collateral damage. The method minimizes trial-and-error in clinical settings, accelerating treatment and improving patient outcomes within the established safety profile of SLT. We demonstrate the viability and potential improvement over existing manual procedures through simulation and retrospective data analysis, projecting significant long-term benefits for glaucoma treatment.

Zenodo (CERN European Organization for Nuclear Research)
Freed–Hardeman University (US)
Openalex Percentile: Top 42%
Glaucoma and retinal disorders
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Automated Spectral Optimization of Selective Trabeculoplasty (SLT) Laser Parameters via Adaptive Bayesian Reinforcement Learning · Zenodo (CERN European Organization for Nuclear Research) (2025) | TGRS Research Map | TGRS