NLR AS DIAGNOSTIC VALUE FOR THE SEVERITY OF ACUTE CHOLANGITIS

Acute cholangitis (AC) is a serious infectious condition in which systemic complications occur and can lead to mortality.Methods: In the retrospective analyses, 411 patients who were followed at the 1st territorial medical as-sociation of Lviv, the medical center of St. Paraskeva, the emergency hospital of Chernivtsi between 2020 and 2024 and met the definitive diagnosis criteria for acute cholangitis according to the Tokyo guidelines 2018 were enrolled as the study group. Results: There was a statistically significant correlation between the severity of cholangitis and the de-gree of lymphocytopenia. Conclusions: The increase in the severity of cholangitis caused an increase in NLR and PLR and a de-crease in lymphocyte count. Regarding these fact, we assume that lymphocyte count and NLR might have a predictive value on this disease severity of acute cholangitis. We recommended the use of lymphocyte count for grading acute cholangitis severity and providing early biliary drainage in patients.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-08-15
DOI
https://doi.org/10.5281/zenodo.16880698
Primary Topic
Gallbladder and Bile Duct Disorders
Type
article
Field-Weighted Citation Impact
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article

NLR AS DIAGNOSTIC VALUE FOR THE SEVERITY OF ACUTE CHOLANGITIS

Zenodo (CERN European Organization for Nuclear Research)
Gallbladder and Bile Duct Disorders
article

NLR AS DIAGNOSTIC VALUE FOR THE SEVERITY OF ACUTE CHOLANGITIS

article en

Abstract

Acute cholangitis (AC) is a serious infectious condition in which systemic complications occur and can lead to mortality.Methods: In the retrospective analyses, 411 patients who were followed at the 1st territorial medical as-sociation of Lviv, the medical center of St. Paraskeva, the emergency hospital of Chernivtsi between 2020 and 2024 and met the definitive diagnosis criteria for acute cholangitis according to the Tokyo guidelines 2018 were enrolled as the study group. Results: There was a statistically significant correlation between the severity of cholangitis and the de-gree of lymphocytopenia. Conclusions: The increase in the severity of cholangitis caused an increase in NLR and PLR and a de-crease in lymphocyte count. Regarding these fact, we assume that lymphocyte count and NLR might have a predictive value on this disease severity of acute cholangitis. We recommended the use of lymphocyte count for grading acute cholangitis severity and providing early biliary drainage in patients.

Zenodo (CERN European Organization for Nuclear Research)
Good health and well-being
Openalex Percentile: Top 38%
Gallbladder and Bile Duct Disorders
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