To Assess the Therapeutic Potential of Quercetin and Vitamin E Based Emulgel for the Treatment of Atopic Dermatitis

Atopic dermatitis (AD) is a long-lasting inflammatory skin disease that shows signs of itching, redness, and skin lesions, which affect the quality of life of patients to a significant degree. The traditional therapies mostly depend on corticosteroids that can lead to side effects upon their extended usage. This paper seeks to evaluate the therapeutic value of a Quercetin and Vitamin E- combined emulgel in managing Atopic dermatitis. A combination of quercetin, a flavonoid (possessing anti-oxidation and anti-inflammatory activities), with Vitamin E, which is a highly effective antioxidant is postulated to be a homeopathic antidote in treatment of AD symptoms. Skin penetration and extended release have been emphasized to provide skin penetration emulgel formulation that helps the active compounds reach their targets efficiently. This paper focuses on the evaluation of the emulgel efficacy in ameliorating AD severity by assessing its efficacy on clinical scales, histopathological analysis, and assessing the levels of inflammatory markers. The findings of this research can offer support in the employment of emulgel containing Quercetin and Vitamin E as supplementary or substitute products of governmental therapies in the treatment of atopic dermatitis.