"Rho-kinase inhibition reduces subretinal fibrosis" IMC dataset

This upload contains the raw and processed IMC dataset from the publication. The files include: Raw IMC dataset in the archive "imc_raw.zip" Segmentation masks for each slide obtained used steinpose napari plugin in "masks.zip", cellpose v2 parameters included Processed with steinbock package raw R dataset in "spe_raw.rds" Manual cell annotation table in "annotation_manual.zip", parameters included Layer annotation QuPath project in "qproject_layers.zip" Fully analyzed R dataset in "spe_final.rds" Analysis script in "project_script.R" Differential abundance and state results in "differential_abundance.xlsx" and "differential_state.xlsx"

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-08-08
DOI
https://doi.org/10.5281/zenodo.16780396
Primary Topic
Retinal Development and Disorders
Type
article
Field-Weighted Citation Impact
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article

"Rho-kinase inhibition reduces subretinal fibrosis" IMC dataset

Zenodo (CERN European Organization for Nuclear Research)
Retinal Development and Disorders
article

"Rho-kinase inhibition reduces subretinal fibrosis" IMC dataset

article en

Abstract

This upload contains the raw and processed IMC dataset from the publication. The files include: Raw IMC dataset in the archive "imc_raw.zip" Segmentation masks for each slide obtained used steinpose napari plugin in "masks.zip", cellpose v2 parameters included Processed with steinbock package raw R dataset in "spe_raw.rds" Manual cell annotation table in "annotation_manual.zip", parameters included Layer annotation QuPath project in "qproject_layers.zip" Fully analyzed R dataset in "spe_final.rds" Analysis script in "project_script.R" Differential abundance and state results in "differential_abundance.xlsx" and "differential_state.xlsx"

Zenodo (CERN European Organization for Nuclear Research)
University of Bern (CH), Harvard University (US), University Hospital of Bern (CH), Affiliated Hospital of Guizhou Medical University (CN), Universitätsklinik für Augenheilkunde (CH)
Openalex Percentile: Top 60%
Retinal Development and Disorders
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