Fast Dissolving Tablet: An Overview

Oral delivery is the preferred route of drug delivery in the pharmaceutical industry because to its safety, convenience, and cost-effectiveness, with high patient compliance. Fast dissolving tablets have become a prevalent and widely recognized dose form, particularly for young patients due to the insufficient development of their muscular and neural systems, as well as for senior individuals experiencing Parkinson’s disease or hand tremors. Nowadays, a small number of solid dosage forms, such as tablets and capsules, have issues such dysphagia, which makes it difficult to swallow. This leads to a high rate of non-compliance and renders the treatment ineffective. Fast dissolving. Tablets dissolve easily in saliva, eliminating the need for water. Fast-dissolving pills dissolve quickly in saliva, often within seconds. Fast dissolving tablet formulations offer advantages over conventional tablet and liquid dosing formats. Various techniques, including spray drying, sublimation, melt granulation, direct compression, freeze-drying/lyophilization, and mass extrusion, have been developed for producing fast dissolving tablets. This review examines the needs, benefits, constraints, and technology used for quick dissolving tablets, as well as evaluation methodologies.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-05-31
DOI
https://doi.org/10.5281/zenodo.15563036
Primary Topic
Advanced Drug Delivery Systems
Type
article
Field-Weighted Citation Impact
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article

Fast Dissolving Tablet: An Overview

Zenodo (CERN European Organization for Nuclear Research)
Advanced Drug Delivery Systems
article

Fast Dissolving Tablet: An Overview

article en

Abstract

Oral delivery is the preferred route of drug delivery in the pharmaceutical industry because to its safety, convenience, and cost-effectiveness, with high patient compliance. Fast dissolving tablets have become a prevalent and widely recognized dose form, particularly for young patients due to the insufficient development of their muscular and neural systems, as well as for senior individuals experiencing Parkinson’s disease or hand tremors. Nowadays, a small number of solid dosage forms, such as tablets and capsules, have issues such dysphagia, which makes it difficult to swallow. This leads to a high rate of non-compliance and renders the treatment ineffective. Fast dissolving. Tablets dissolve easily in saliva, eliminating the need for water. Fast-dissolving pills dissolve quickly in saliva, often within seconds. Fast dissolving tablet formulations offer advantages over conventional tablet and liquid dosing formats. Various techniques, including spray drying, sublimation, melt granulation, direct compression, freeze-drying/lyophilization, and mass extrusion, have been developed for producing fast dissolving tablets. This review examines the needs, benefits, constraints, and technology used for quick dissolving tablets, as well as evaluation methodologies.

Zenodo (CERN European Organization for Nuclear Research)
Openalex Percentile: Top 60%
Advanced Drug Delivery Systems
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