Comparison Between Bladder and Rectal Dose using Single and Three Channel Vaginal Applicator in HDR Electronic Brachytherapy

Dosage distributions and compliance with recommended limits for the vagina, bladder, and rectum are themain subjects of the analysis. The results show that all evaluated organs had notable departures from the recommendeddosage levels. The vagina had significant dose escalation in the single-channel method, exceeding 4000 cGy, and thedoses administered to the bladder and rectum were significantly higher than the recommended limits. The three-channelapplicator also demonstrated dose escalation patterns in the rectum and bladder, significantly above the planned limits.The necessity of careful treatment planning and optimization to guarantee safer operations for these vital organs ishighlighted by these increased dosages. The comparison highlights the need for thorough dose adjustment in HDRelectronic brachytherapy by highlighting recurring patterns of increased doses in the bladder and rectum. Importantinformation about organ-specific dose analyses is revealed by comparing single-channel and three-channel vaginalapplicators in HDR electronic brachytherapy. Examined in the framework of recommended limitations, the vaginal,bladder, and rectal dosages provide important insights into the effectiveness and compliance of this treatment approach.The vaginal analysis for the single-channel method showed dosage variations, noticeably higher than desired levels. Thehighest dose significantly exceeded the targeted dose, creating some dangers even if it met some limits. Dosesconsiderably beyond recommended limits were found in the bladder and rectal tests, highlighting the significance ofcareful planning for safer treatments. Comparing organ doses within certain parameters provides information on theeffectiveness of HDR electronic brachytherapy. Although vaginal doses met DV% targets (>95%), there were significantdifferences between targeted Dmax (700 cGy) and actual Dmax (4387.4 cGy), which raised concerns about escalatingdoses. With a noticeably high Dmax of 1541.0 cGy, bladder doses exceeded D0.1 cm³ (1353 cGy vs. <11000 cGy) butfell below D2 cm³ limitations. The hazards associated with Dmax at 1853.0 cGy were highlighted by rectal dosages thatalso exceeded limits. Both the bladder and the rectum in three-channel applicators surpassed recommended limits in alltested parameters, indicating elevated hazards over and beyond the 700 cGy dosage that was planned. When comparingsingle and three-channel vaginal applicators in HDR electronic brachytherapy, significant departures from therecommended vaginal, bladder, and rectum restrictions are observed. In key organs, both methods demonstratedincreased doses, highlighting the necessity of careful treatment planning and dose optimization to guarantee safer andmore efficient brachytherapy treatments.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-02-15
DOI
https://doi.org/10.5281/zenodo.15666469
Primary Topic
Advanced Radiotherapy Techniques
Type
article
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article

Comparison Between Bladder and Rectal Dose using Single and Three Channel Vaginal Applicator in HDR Electronic Brachytherapy

Zenodo (CERN European Organization for Nuclear Research)
Advanced Radiotherapy Techniques
article

Comparison Between Bladder and Rectal Dose using Single and Three Channel Vaginal Applicator in HDR Electronic Brachytherapy

article en

Abstract

Dosage distributions and compliance with recommended limits for the vagina, bladder, and rectum are themain subjects of the analysis. The results show that all evaluated organs had notable departures from the recommendeddosage levels. The vagina had significant dose escalation in the single-channel method, exceeding 4000 cGy, and thedoses administered to the bladder and rectum were significantly higher than the recommended limits. The three-channelapplicator also demonstrated dose escalation patterns in the rectum and bladder, significantly above the planned limits.The necessity of careful treatment planning and optimization to guarantee safer operations for these vital organs ishighlighted by these increased dosages. The comparison highlights the need for thorough dose adjustment in HDRelectronic brachytherapy by highlighting recurring patterns of increased doses in the bladder and rectum. Importantinformation about organ-specific dose analyses is revealed by comparing single-channel and three-channel vaginalapplicators in HDR electronic brachytherapy. Examined in the framework of recommended limitations, the vaginal,bladder, and rectal dosages provide important insights into the effectiveness and compliance of this treatment approach.The vaginal analysis for the single-channel method showed dosage variations, noticeably higher than desired levels. Thehighest dose significantly exceeded the targeted dose, creating some dangers even if it met some limits. Dosesconsiderably beyond recommended limits were found in the bladder and rectal tests, highlighting the significance ofcareful planning for safer treatments. Comparing organ doses within certain parameters provides information on theeffectiveness of HDR electronic brachytherapy. Although vaginal doses met DV% targets (>95%), there were significantdifferences between targeted Dmax (700 cGy) and actual Dmax (4387.4 cGy), which raised concerns about escalatingdoses. With a noticeably high Dmax of 1541.0 cGy, bladder doses exceeded D0.1 cm³ (1353 cGy vs. <11000 cGy) butfell below D2 cm³ limitations. The hazards associated with Dmax at 1853.0 cGy were highlighted by rectal dosages thatalso exceeded limits. Both the bladder and the rectum in three-channel applicators surpassed recommended limits in alltested parameters, indicating elevated hazards over and beyond the 700 cGy dosage that was planned. When comparingsingle and three-channel vaginal applicators in HDR electronic brachytherapy, significant departures from therecommended vaginal, bladder, and rectum restrictions are observed. In key organs, both methods demonstratedincreased doses, highlighting the necessity of careful treatment planning and dose optimization to guarantee safer andmore efficient brachytherapy treatments.

Zenodo (CERN European Organization for Nuclear Research)
Bangladesh Islami University (BD)
Good health and well-being
Openalex Percentile: Top 45%
Advanced Radiotherapy Techniques
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