Dermatitis Neglecta Should be Considered as One of the Differential Diagnoses for Acanthosis Nigricans

Acanthosis nigricans is a skin condition that often indicates an underlying health issue. It typically appears inareas such as the nape, armpits, and groin, presenting as velvety patches of hyperpigmentation with irregular borders. Thiscondition is most frequently linked to diabetes and insulin resistance, though it can occasionally signal the presence ofinternal malignancies. Additionally, it may arise from hormonal disorders or the use of specific medications, includingsystemic glucocorticoids and oral contraceptives. This activity aims to review the diagnostic evaluations and treatmentoptions for acanthosis nigricans while emphasizing the importance of an interprofessional approach in assessing andmanaging patients with this condition. Acanthosis nigricans is commonly observed in individuals under the age of 40 andis often linked to several conditions, including obesity, hypothyroidism, acromegaly, polycystic ovary syndrome, insulinresistant diabetes, and both Cushing's and Addison's diseases. Additionally, it may be associated with rare conditions suchas pinealoma, Cushing's disease, ovarian hyperthecosis, stromal luteoma, ovarian dermoid cysts, Prader-Willi syndrome,leprechaunism, lipoatrophic diabetes, pineal hyperplasia syndrome, and Alstrom syndrome. In relation to our case report,it is important to consider dermatitis neglecta as one of the differential diagnoses for acanthosis nigricans. Dermatitisneglecta is an inflammatory skin condition that may arise when an individual is unable to maintain adequate personalhygiene. Regular bathing is essential for preserving skin cleanliness and promoting overall health. Engaging in bathing andscrubbing routines facilitates the removal of germs, oils, and dead skin cells. Prolonged intervals without bathing can leadto the accumulation of these substances on the skin, potentially resulting in a dense, hyperpigmented crust. While dermatitisneglecta is less common than other skin conditions with similar symptoms, a thorough assessment of an individual'ssymptoms and risk factors is crucial for accurate diagnosis and effective treatment of dermatitis neglecta.